4BI1

Excretion

Structures and Functions in Living Organisms · 6 question types

Exam Frequency Analysis

Past paper frequency (2018 to 2024)

This topic accounts for approximately 12% of your exam marks.

stable
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Stable12%

The kidney and urea production appear regularly; dialysis is a common application question.

The nephron is the functional unit of the kidney: every step of urine formation happens along its length. A single nephron has these parts, in order along the route the filtrate takes:

  1. Bowman's capsule: a cup-shaped structure in the cortex that surrounds the glomerulus, a tight knot of capillaries. The Bowman's capsule is where blood is filtered (, section 6).
  2. Proximal convoluted tubule (PCT): a coiled tube also in the cortex. of glucose happens here.
  3. Loop of Henle: a long hairpin loop that dips deep down into the medulla and back up. Reabsorbs some water and salts.
  4. Distal convoluted tubule (DCT): a second coiled tube, back in the cortex. Fine-tunes the salt content of the filtrate.
  5. Collecting duct: runs back down through the medulla to the renal pelvis. The site of most water reabsorption, controlled by the hormone (section 7).

Around each nephron runs a dense network of capillaries that picks up the substances reabsorbed from the filtrate and returns them to the bloodstream.

A labelled diagram of a single nephron showing the glomerulus inside the Bowman's capsule, the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule and the collecting duct
Source: Nephron Structure by Save My Exams