BiologyExam code: 4BI1

Excretion

Structures and Functions in Living Organisms

The nephron is the functional unit of the kidney: every step of urine formation happens along its length. A single nephron has these parts, in order along the route the filtrate takes:

  1. Bowman's capsule: a cup-shaped structure in the cortex that surrounds the glomerulus, a tight knot of capillaries. The Bowman's capsule is where blood is filtered (, section 6).
  2. Proximal convoluted tubule (PCT): a coiled tube also in the cortex. of glucose happens here.
  3. Loop of Henle: a long hairpin loop that dips deep down into the medulla and back up. Reabsorbs some water and salts.
  4. Distal convoluted tubule (DCT): a second coiled tube, back in the cortex. Fine-tunes the salt content of the filtrate.
  5. Collecting duct: runs back down through the medulla to the renal pelvis. The site of most water reabsorption, controlled by the hormone (section 7).

Around each nephron runs a dense network of capillaries that picks up the substances reabsorbed from the filtrate and returns them to the bloodstream.

A labelled diagram of a single nephron showing the glomerulus inside the Bowman's capsule, the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule and the collecting duct
Source: Nephron Structure by Save My Exams

Common exam question

Identifying structures on a kidney or nephron diagram

Question: Identify labelled structures on a diagram of the urinary system, a kidney section or a nephron, usually as one-mark multiple-choice items: the Bowman's capsule, loop of Henle or proximal convoluted tubule, where ultrafiltration happens, where glucose is reabsorbed, or which structure ADH affects (1 mark each).

Asked in 6 of the 23 papers. Know the nephron in filtrate order: the cup-shaped Bowman's capsule around the glomerulus (ultrafiltration); the first coiled tube, the proximal convoluted tubule (glucose reabsorbed); the hairpin loop of Henle in the medulla; the second coil, the distal convoluted tubule; then the collecting duct, which ADH acts on. On a whole-kidney section the renal artery and vein carry blood; only the ureter carries urine.

The ureter runs from kidney to bladder; the urethra leaves the bladder. One scheme rejects "urethra" for the ureter (a phonetic spelling that cannot be confused with it is allowed) and "gall bladder" for the bladder.

Build on this topic