4BI1

Genetic Engineering

Use of Biological Resources · 6 question types

Exam Frequency Analysis

Past paper frequency (2018 to 2024)

This topic accounts for approximately 10% of your exam marks.

increasing
Medium
Increasing10%

Insulin production by bacteria and GM crops are growing in exam frequency.

This is the last topic in the biology syllabus. Bringing together everything from topics 12, 17 and 18, modern biotechnology offers a toolkit of techniques for producing useful plants, animals and proteins:

TechniqueWhat it producesSpeedGenetic variation in result
Selective breedingNew breed/variety with desired traitsSlow (many generations)Some (mix of parents' alleles)
Cuttings (topic 12)Identical plants from a single parentFastNone (clones)
Tissue culture / micropropagation (topic 17)Many identical plant clones from one parentVery fastNone (clones)
Genetic engineeringOrganism with a specific new traitFast (at lab stage)None (precise control)
Cloning animalsGenetically identical animal copiesSlow (per individual), but each is a cloneNone (clones)
Industrial fermentationLarge quantities of microbial product (e.g. yoghurt, insulin)FastPopulation grown from one strain

Each technique has its place. Together, they have completely transformed how humans produce food, medicines and industrial materials, and they continue to develop rapidly. The biggest challenges going forward are not really technical but ethical, regulatory and social: how to deploy these powerful tools wisely, equitably, and with appropriate caution.